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When it comes to arthritis, some joints seem to get all the attention. We talk about knees and hips an awful lot. Our knees and hips must work well for walking, and a third or more of adults over age 65 develop osteoarthritis in these joints, resulting in over a million joint replacements in the US each year.

But what about the first carpometacarpal joint that connects your thumb to your wrist? That’s surprisingly important, yet most people can’t name it and only become aware of it once it becomes arthritic. Fortunately, research recently confirmed that a common therapy requiring no medication can effectively treat this type of arthritis.

Known more simply as the first CMC joint, it allows us to move our thumb through a wide range of motion. If you appreciate the many uses of opposable thumbs, you can thank the first CMC joint! Having opposable thumbs allows us to grasp objects, open jars, turn doorknobs, write, make a tight fist, turn a key, and perform countless other everyday activities.

That’s why the first CMC joint may be the most underappreciated joint in the body.

Your doctor may suspect osteoarthritis of the first CMC based on your symptoms and physical examination, but an x-ray can confirm the diagnosis.

Treatment options for osteoarthritis of any joint, including the first CMC, are limited. And they don’t always work well. In the most recent US guidelines for hand or thumb osteoarthritis, only the following are strongly recommended:

A brace, exercise, and education are typically provided through occupational therapy, a form of physical therapy focused on hand and wrist functions essential to activities of daily life, such as bathing or getting dressed. Yet, the impact of occupational therapy had not been comprehensively evaluated.

The study enrolled 180 people with first-CMC osteoarthritis. Their average age was 63 and 80% were women.

Half were randomly assigned to receive occupational therapy (including education, exercises, braces, and assistive devices) while the other half only received information about osteoarthritis.

The results demonstrated that a three-month course of occupational therapy effectively relieved pain at rest and after exercise, and improved grip strength and function.

This study is among the best research evaluating occupational therapy for this condition. However, it had some limitations. Treatment assignments were not blinded: participants knew if they received occupational therapy or not, so expectations and the impact of the placebo effect could have affected the results. The study lasted just three months, so the impact of occupational therapy over the long term was not assessed.

Despite how common this form of osteoarthritis is and how much trouble it causes, many questions remain. It would be helpful to know:

If you live long enough, chances are good that you’ll develop osteoarthritis of the joint that helps make the amazing opposable thumb work smoothly. Hopefully, we’ll have better treatments before that happens. Though it’s reassuring that occupational therapy can help, the holy grail for anyone who might develop osteoarthritis is a treatment to prevent it, stop it from getting worse, or even reverse its damage. Fortunately, there are researchers hard at work to discover such treatments.

Robert H. Shmerling, MD , Senior Faculty Editor, Harvard Health Publishing

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No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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